Which drug is classified along with bisphosphonates, cyclosporine, lithium, and topiramate based on the memory aid MR. F?

• A. Digoxin
• B. Levothyroxine
• C. Fluoxetine
• D. Fentanyl

Answer: (A)

The correct choice, Digoxin, is linked to the mnemonic MR. F because it is known to be one of the drugs that have a risk of causing renal toxicity and can be affected by renal function. The mnemonic helps to categorize medications that require careful monitoring of renal function due to their potential for accumulation and toxicity in patients with compromised kidney function.

Bisphosphonates, cyclosporine, lithium, and topiramate are all included in this mnemonic as they are also medications that necessitate monitoring of renal function. Each of these drugs can have significant complications if not properly managed in patients with renal issues. For instance, bisphosphonates can lead to osteonecrosis of the jaw, cyclosporine can cause nephrotoxicity, lithium can result in toxicity due to impaired renal clearance, and topiramate is implicated in metabolic acidosis, particularly when renal function is altered.

The other medications listed in the choices do not fall under this category because they do not share the same level of concern regarding renal toxicity in the context of this mnemonic. Therefore, Digoxin aligns with the other medications categorized under MR. F due to its significance in renal monitoring practices.