Which of the following is included in the Beta-1 selective blockers mnemonic?

• A. Propranolol
• B. Metoprolol
• C. Amlodipine
• D. Carvedilol

Answer: (B)

Beta-1 selective blockers, also known as cardioselective beta-blockers, primarily target the beta-1 adrenergic receptors found mainly in the heart. This selectivity is important for minimizing adverse effects on other adrenergic receptors, particularly those found in the lungs, which are associated with beta-2 receptors.

Metoprolol is a prime example of a beta-1 selective blocker that is commonly used in clinical practice for managing conditions such as hypertension, heart failure, and angina. The effectiveness of metoprolol in reducing heart rate and myocardial contractility makes it a preferred choice in patients with cardiovascular issues. It’s important to note that it demonstrates minimal effects on beta-2 receptors, making it safer for patients with respiratory conditions like asthma.

In contrast, propranolol, while a well-known beta-blocker, is a non-selective agent that affects both beta-1 and beta-2 receptors, which can lead to bronchoconstriction in susceptible individuals. Amlodipine, on the other hand, is a calcium channel blocker and does not fit into the category of beta-blockers. Carvedilol is a mixed blocker that has both beta-1 and beta-2 blocking properties, and it also