Which of the following statements about the mnemonic PS PORCS is correct?

• A. It includes natural products that are anticoagulants
• B. It identifies CYP inducers
• C. It refers to drugs that require a filter
• D. It is used for drugs that should not be refrigerated

Answer: (B)

The mnemonic PS PORCS is specifically used to identify CYP inducers. CYP inducers are substances that enhance the activity of cytochrome P450 enzymes, leading to increased metabolism of drugs. This can result in reduced levels of the affected drugs, which might necessitate dose adjustments to maintain therapeutic efficacy.

Each letter in the mnemonic corresponds to a specific CYP inducer: for example, "P" stands for phenytoin, "S" for St. John's Wort, and so on. Recognizing these drug interactions is crucial for patient safety and effective medication management.

The other options do not align with the function of this mnemonic. While natural products and filters are important in pharmacology, they are not what PS PORCS is intended to help remember. Similarly, refrigeration considerations pertain to drug storage rather than CYP enzyme interactions. Therefore, understanding that PS PORCS relates solely to CYP inducers highlights its importance in a clinical context.